Give the body a blueprint to heal itself.

Dimension Bio is a biotechnology company pioneering regenerative therapeutics. We design, develop, and manufacture solutions that restore tissue function lost to disease, trauma or aging.

Biomaterials, Reimagined.

Restoring tissue function requires coordinated interactions across biological length scales, from cellular microenvironments to the surrounding tissue.

Our bioinspired platform, BioNidum™, fuses materials science, 3D printing, and digital manufacturing to engineer regenerative microenvironments that influence cell behavior, tissue organization, and ultimately healing.

The platform’s flexibility supports the development of implantable and injectable products tailored to the unique demands of different tissues and clinical applications.

Unlock the potential of biosynthetic and biohybrid scaffolds.

BioNidum creates the conditions needed for durable healing by activating the body’s natural repair processes.

The platform provides independent control of material composition, three-dimensional architecture, and microstructure, delivering a level of design flexibility not achievable with conventional manufacturing approaches. The resulting interconnected porous architecture promotes vascularization, cell infiltration and tissue integration, and remodeling. At the same time, the platform allows precise tuning of mechanical performance, degradation behavior, and surgical handling to meet the needs of each indication.

A protected platform for next-gen product development. BioNidum is backed by a robust patent estate and proprietary manufacturing capabilities and know-how that span biomaterial compositions, 3D-printable inks, multi-material and biohybrid constructs, tissue repair applications, and cell delivery systems.

Tissue Regeneration & Restoration

Our platform enables regenerative products across large clinical markets, including sports medicine, orthopedics, plastic and reconstructive surgery, aesthetics, dental, and neuro/spine.

BioNidum serves as the foundation for a growing pipeline of implantable and injectable biosynthetic products developed both internally and with strategic partners.

Cell Delivery & Replacement

BioNidum scaffolds can also be combined with therapeutic cells to create implantable cell therapies for liver failure, Type 1 diabetes, and other diseases characterized by loss of organ function.

By creating supportive regenerative environments, BioNidum helps implanted cells survive, integrate, vascularize, and function over time.

Team

Leadership

Caralynn Nowinski Collens, M.D.
Co-founder & CEO

Ramille Shah, Ph.D.
Co-founder & CSO

Larry Weinstein
SVP, Manufacturing & Quality Operations

Cole Johnson, Ph.D.
SVP, Corporate Development

Board of Directors

Caralynn Nowinski Collens, M.D.
Director

Ramille Shah, Ph.D.
Director

Rima Chakrabarti, M.D.
Director

Heidi Hagen
Director

Amy Kruse, Ph.D.
Director

Ayush Jain
Observer

Isaiah Reeves, Ph.D.
Observer

Clinical Advisory Board

Melissa Palmer, MD (Chair)

Jasmohan Bajaj, MD

Anil Dhawan, MD

Suthat Liangpunksakul, MD, MPH

Travis Manasco, MD

Vijay Shah, MD

Wing-Kin Syn, MD, PhD

Scientific Advisory Board

Salman Khetani, PhD

Jane Lebkowski, PhD

Lonnie Shea, PhD

Doris Taylor, PhD

Strategic Advisors

Andy Christensen

Chris Ehrlich

Ritu Shah

Co-Founder

Adam Jakus, Ph.D.

Recent Press

November 19, 2025

November 12, 2025

November 5, 2025

September 23, 2025

August 27, 2025

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February 1, 2023

Interested in joining our team?

We believe that innovation drives disruptive and unexpected solutions. In that spirit, we take risks, pushing boundaries but always guided by science. We seek out and have deep respect for unique expertise and diverse perspectives.

We collaborate to inspire and create solutions that matter. We use our experience, expertise, and creativity to create value. We are good partners who do what we say we are going to do.

We seek to build our team with similarly driven individuals.

Have questions?