Inspired by biology. Engineered for Healing.
Dimension Bio is a biotechnology company pioneering regenerative therapeutics. We design lifesaving solutions that restore organ function lost to disease, trauma or aging.
Cells alone are not enough.
The surrounding environment plays a key role in directing cell behavior. Cell functionality requires complex nano-, micro-, and macro-interactions with surrounding tissues. We combine cells and biomaterials in a three-dimensional matrix designed to overcome key challenges in cell therapy.
Our bioinspired cell delivery system, BioNidum™, fuses materials science, 3D-printing, and digital manufacturing to transform cells into implantable, tissue-like therapies.
Unlock the curative potential of cell therapies.
By providing a three-dimensional architecture that promotes rapid vascularization and seamless tissue integration, our tissue therapeutics create the conditions cells need to survive, function, and persist.
The result is a more durable and effective therapeutic response—unlocking the curative potential of cell therapies.
Tissue Therapeutics Pipeline
Our lead program targets liver failure, providing immediate supplemental liver function to stabilize patients in crisis. By enabling the native liver to recover, it offers an alternative to transplant and fills a critical gap for those with limited treatment options.
BioNidum System Validation
The BioNidum System is being used in multiple therapeutic products today, including one clinical-stage product and three partnered products in development.
Team
Leadership
Caralynn Nowinski Collens, M.D.
Co-founder & CEO
Ramille Shah, Ph.D.
Co-founder, CSO, Head of Platform R&D
Larry Weinstein
SVP, Manufacturing & Operations
Cole Johnson, Ph.D.
SVP, Corporate Development
Rafal Witek, Ph.D.
VP, Translational R&D, Head of Liver Program
Austin Srejma
Chief of Staff & VP Portfolio Strategy
Board
Caralynn Nowinski Collens, M.D.
Director
Ramille Shah, Ph.D.
Director
Rima Chakrabarti, M.D.
Director
Amy Kruse, Ph.D.
Director
Ayush Jain
Observer
Isaiah Reeves, PhD
Observer
Advisors
Chris Ehrlich
Doris Taylor, Ph.D., DSc (H), FACC, FAHA
Lonnie Shea, Ph.D.
Salman Khetani, Ph.D.
Ritu Shah
Andy Christensen
Co-Founder
Adam Jakus, Ph.D.
Recent Press
May 8, 2025
May 6, 2025
February 4, 2025
November 15, 2024
August 27, 2024
July 23, 2024
February 21, 2024
October 4, 2023
February 2, 2023
February 1, 2023
Interested in joining our team?
We believe that innovation drives disruptive and unexpected solutions. In that spirit, we take risks, pushing boundaries but always guided by science. We seek out and have deep respect for unique expertise and diverse perspectives.
We collaborate to inspire and create solutions that matter. We use our experience, expertise, and creativity to create value. We are good partners who do what we say we are going to do.
We seek to build our team with similarly driven individuals.